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FORMULATION FOR ANTIBODY AND DRUG CONJUGATE THEREOF
专利权人:
发明人:
申请号:
EP17702300.9
公开号:
EP3402465A1
申请日:
2017.01.13
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Disclosed herein are surfactant free antibody and antibody-drug-conjugate (ADC) formulations for anti-AXL antibodies and ADCs, including aqueous formulations, lyophilized formulations, and reconstituted formulations, as well as related processes and uses. The formulations are particularly suitable for an anti-AXL ADC based on an auristatin or DM1 derivative or other similarly hydrophobic drugs. Some formulations comprise histidine and mannitol.
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