LOWERY, DAVID E.,KENNEDY, MICHAEL J.,FULLER, TROY E.
申请号:
AU2013201266
公开号:
AU2013201266A1
申请日:
2013.03.01
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
An attenuated Pasteurellaceae bacterium selected from the group consisting of Pasteureila (Mannheimia) haemolytic, Pasteureila muitocida, and Actinohacillus pleuropnetunoniae comprising a mutation in a polynucleotide sequence that encodes a fhaC polypeptide comprising an amino acid sequence at least 70% identical to thefhaC amino acid sequence of SEQ ID NO: 20, wherein the mutation results in decreased virulence and attenuation of the bacterium.