NOVEL BISPHOSPHONIC ACID DERIVATIVE AND APPLICATION FOR SAME

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专利权人:

发明人:

申请号：

EP15870103.7

公开号：

EP3235822A1

申请日:

2015.12.18

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The novel bisphosphonic acid ester derivatives represented by the following formula (1):        Y-Cy-(NH)m-(CH2)n-C(X)(PO(OR1)(OR2))2     (1)wherein each symbol is as defined in the DESCRIPTION, which has an amino group substituted by a heterocyclic group or a heterocyclic group containing a nitrogen atom, and the acid moiety is esterified with a POM group, an n-butanoyloxymethyl (BuOM) group and the like, exhibit a superior direct or indirect cytotoxicity effect on tumor cells and virus infected cells.

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中国工程科技知识中心

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http://www.ckcest.cn/home/