Embodiments of the invention include methods, systems, and computer program products for determining stroke onset. Aspects of the invention include determining a baseline behavioral model for a user and receiving real-time user data from a personal portable device. Aspects of the invention also include analyzing the real-time user data to determine the presence of an abnormal event. Aspects of the invention also include, based at least in part on a determination that the abnormal event is present, conducting a plurality of stroke analyses to generate a plurality of impairment characteristics. Aspects of the invention also include integrating the plurality of impairment characteristics, comparing the integrated plurality of impairment characteristics to the baseline behavioral model and outputting a stroke onset determination.