Alma Mater Studiorum Universita' di Bologna;Alma Mater Studiorum Universita di Bologna
发明人:
Campadelli, Maria Gabriella,Gatta, Valentina
申请号：
AU2016217906
公开号：
AU2016217906A1
申请日:
2016.02.11
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The present invention relates to the field of disease therapy. More specifically, it relates to a retargeted herpesvirus having a heterologous polypeptide fused to glycoprotein H, wherein the polypeptide targets diseased cells. It also relates to a nucleic acid comprising the genome of the herpesvirus of the invention, a vector comprising this nucleic acid and a cell comprising the nucleic acid or the vector. It further relates to killing cells using the herpesvirus of the invention and to methods for growing it in vitro.
