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用於組合療法的藥物組合物
专利权人:
INTERCEPT PHARMACEUTICALS, INC.;英特塞普特醫藥品公司
发明人:
PRUZANSKI, Mark,ADORINI, Luciano,ADORINI, Luciano,盧西亞諾‧阿多里尼
申请号:
HK18105766.1
公开号:
HK1246191A
申请日:
2018.05.04
申请国别(地区):
HK
年份:
2018
代理人:
摘要:
The present invention relates to a pharmaceutical composition comprising a combination of an FXR agonist and at least one lipid lowering agent (e.g., PPAR-alpha agonist, PPAR-delta agonist, PPAR-alpha and delta dual agonist, and/or statin). Also disclosed is use of the combination for the treatment or prevention of a FXR mediated disease or condition, such as primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), portal hypertension, bile acid diarrhea, NAFLD (nonalcoholic fatty liver disease), NASH (non-alcohol-induced steatohepatitis), and other chronic liver diseases. The combination of the present invention is useful for the treatment or prevention of conditions related to elevated lipid and liver enzyme levels. The present invention also relates to packs or kits including the pharmaceutical combination.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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