Christopher DALY,Gavin THURSTON,Nicholas J. PAPADOPOULOS
申请号：
US13925923
公开号：
US20130344093A1
申请日:
2013.06.25
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides antibodies that bind to EGFR and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human EGFR with high affinity. In certain embodiments, the antibodies of the present invention are capable of inhibiting the growth of tumor cells expressing high levels of EGFR and/or inducing antibody-dependent cell-mediated cytotoxicity (ADCC) of such cells. The antibodies of the invention are useful for the treatment of various cancers as well as other EGFR-related disorders.
