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Inhibitors of NCCa-ATP channels for therapy
专利权人:
J. Marc Simard
发明人:
J. Marc Simard
申请号:
US12665853
公开号:
US08557867B2
申请日:
2008.06.20
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Methods and compositions are provided that are utilized for treatment and/or prevention of intraventricular hemorrhage or progressive hemorrhagic necrosis (PHN), particularly following spinal cord injury. In particular, the methods and compositions are inhibitors of a particular NCca-ATP channel and include, for example, inhibitors of SUR1 and/or inhibitors of TRPM4. Kits for treatment and/or prevention of intraventricular hemorrhage or progressive hemorrhagic necrosis (PHN), particularly following spinal cord injury, are also provided. The present invention also concerns treatment and/or prevention of intraventricular hemorrhage in infants, including premature infants utilizing one or more inhibitors of the channel is provided to the infant, for example to brain cells of the infant.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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