A photo-ultrasonic biostimulation device and method of use for treating internal organ dysfunction and failure by restoring homeostasis and reversing generalized cell, tissue, and organ inflammation and edema throughout the VAST and thereby supporting the healthy functional automaticity of the body. This is achieved by the controlled exposure of the mitochondria, cells, tissues, and organ in the VAST, including the organs and tissues exhibiting dysfunction and the interdependent organs, with the precise dosimetry of the synergetic combination of specific wavelengths and tolerances of electromagnetic and ultrasonic energy. Such medical device is to be used concurrently with standard best medical practices of diagnosis and treatment and is designed to supplement and significantly improve outcomes.
