DACOSTA, Ralph,GIBSON, Christopher,OTTOLINO-PERRY, Kathryn,ANANTHA, Nayana Thalanki,DONE, Susan Jane,LEONG, Wey-Liang,EASSON, Alexandra M.
申请号：
AU2019215811
公开号：
AU2019215811A1
申请日:
2019.02.01
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
A method of assessing surgical margins is disclosed. The method includes, subsequent to administration of a compound configured to induce emissions of between about 600 nm and about 660 nm in cancerous tissue cells, positioning a distal end of a handheld, white light and fluorescence-based imaging device adjacent to a surgical margin. The method also includes, with the handheld device, substantially simultaneously exciting and detecting autofluorescence emissions of tissue cells and fluorescence emissions of the induced wavelength in tissue cells of the surgical margin. And, based on a presence or an amount of fluorescence emissions of the induced wavelength detected in the tissue cells of the surgical margin, determining whether the surgical margin is substantially free of at least one of precancerous cells, cancerous cells, and satellite lesions. The compound may be a non-activated, non-targeted compound such as ALA.
