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Derivatives of 5-pyridinyl-1-azabicyclo(3.2.1)octane, preparation method thereof and use of same in therapeutics
专利权人:
Sanofi-Aventis
发明人:
Lochead, Alistair,Leclerc, Odile,Vache, Julien,Galli, Frederic
申请号:
AU2006281341
公开号:
AU2006281341B2
申请日:
2006.08.07
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention relates to compounds having general formula (I), wherein R representsa group that is selected from pyrazolyl, imidazolyl, triazolyl, oxazolyl, oxadiazolyl,thiazolyl, isothiazolyl, thiadiazolyl, tetrazolyl, said group being optionallysubstituted by one or more groups selected from among halogen atoms, groups (C-C)alkyl,(C-C)alkoxy, trifluoromethoxy, trifluoromethyl,nitro, cyano, hydroxy, amino, (C-C)alkylamino or di(C-C)alkylamino,with a single or double carbon-carbon bond between positions 3 and 4 of the azabicyclooctanering; in the form of a base, an acid addition salt, a hydrate or a solvate. The inventionalso relates to the method of preparing said compounds and to the use of same intherapeutics.
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