Robert Henk Henning,Gerrit Jan Willem Euverink,Guido Krenning,Adrianus Cornelis Van der Graaf
申请号：
US16640761
公开号：
US20200206235A1
申请日:
2018.08.23
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to the (S) enantiomeric form of certain 6-chromanol derivatives for use as a medicament. Especially, the present invention relates to the (S) enantiomeric form of a 6-chromanol derivative for use as a medicament wherein said 6-chromanol derivative is chosen from the group consisting of (6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(piperazin-1-yl)methanone； N-(benzyl)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamide； N-(phenyl)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamide； methyl 4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamido)benzoate； (6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(morpholino)methanone, and pharmaceutically acceptable salts or bases thereof and pharmaceutically acceptable salts thereof.
