Joon Won LEE,Yeon Kyeong SHIN,Hye Young KANG,Kwang Woo KIM,So Young KIM,Su Jung KIM,Jun Seok OH,Won Yong HAN
申请号:
US16477187
公开号:
US20190343956A1
申请日:
2018.01.10
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed is a stable liquid formulation, comprising an antibody or antigen-binding portion thereof, an acetate buffer, glycine, and a surfactant, wherein the stable liquid formulation does not comprise at least one of sugar, a sugar alcohol and a metal salt, and the stable liquid formulation is still stable even upon high antibody content, and is superior in osmolality and viscosity, and subcutaneous administration thereof is possible.