Disclosed is a use of a polysaccharide extract ofAstragalusmembranaceusin the preparation of a medicament for enhancing the effect of an immunotherapy for cancer. Also disclosed is a use of a polysaccharide extract ofAstragalusmembranaceusin the preparation of a medicament for increasing a subject’s pool of M1 macrophages, wherein the subject is suffering from one or more conditions associated with undesirable M2 macrophage activation.本發明揭示黃耆多醣萃取物在製備用於增強癌症免疫療法的功效的藥物的用途。本發明亦揭示黃耆多醣萃取物在製備用於在一個體中增加M1巨噬細胞池的藥物的用途，其中該個體患有一或多種與不期望的M2巨噬細胞活化有關的病症。
