Invention for determining a patient's adherence to various prescribed medications. Here a variety of different types of patient pulse wave measurements (blood pressure, pulse oximeter, ECG) and other physiological measurements are obtained. This actual data is compared to calculated measurements that would be expected based on the various patient baseline measurements in the absence of medication, schedule of medications, and impact of medications the various patient baseline measurements. If the actual data meets expectations, then the patient is likely adhering to the regime. Depending on which types of data do not meet expectations, non-adherence to various previously described medications may be reported. Other types of patient physiological readings, such as temperature, motion, lung function, brain wave function (EEG) and the like may also be obtained, and these additional types of readings can be used to extend the range of different types of drugs/medications that the invention can successfully monitor.
