The preparation method system of the taken off Samson St Johswort tunning of the present invention must utilize again the Samson St Johswort dregs of a decoction used, and fermentation reaction is carried out using it as raw material, and obtain Samson St Johswort tunning, reach reduction production be made originally, carbon reduction the effect of. And the Samson St Johswort tunning system for penetrating above method gained has the ability for inhibiting PECTORAL LIMB SKELETON hyperplasia and differentiation, and, through zoopery the results show that the Samson St Johswort tunning system that the present invention takes off all has significant inhibiting effect to fatty liver caused by what high-carbonhydrate diet, adipose tissue accumulation, triglyceride, cholesterol and hepatitis. Accordingly, taken off Samson St Johswort tunning of the invention system has the effect of prevention or the obesity for the treatment of organism, hyperlipemia, cardiovascular disease, diabetes or fatty liver etc. and obesity-related disease.本發明所揭元寶草發酵產物之製備方法係得將已使用過之元寶草藥渣再次利用,以之作為原料進行發酵反應,而獲得元寶草發酵產物,達到降低產製成本、節能減碳之功效。而透過上述方法所得之元寶草發酵產物係具有抑制前脂肪細胞增生及分化之能力,並且,透過動物實驗之結果顯示,本發明所揭之元寶草發酵產物係對於高糖飲食所引起之脂肪肝、脂肪組織堆積、三酸甘油脂、膽固醇及肝炎皆具有顯著的抑制作用。據此,本發明所揭元寶草發酵產物係具有預防或治療生物體之肥胖、高血脂症、心血管疾病、糖尿病或脂肪肝等與肥胖相關疾病之功效。