ALAN M. FOGELMAN,GATTADAHALL M. ANANTHARAMAIAH,MOHAMAD NAVAB
申请号:
BRPI0412981
公开号:
BRPI0412981A2
申请日:
2004.08.10
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
This invention provides novel peptides that ameliorate one or more symptoms of atherosclerosis. The peptides are highly stable and readily administered via an oral route. The peptides are effective to stimulate the formation and cycling of pre-beta high density lipoprotein-like particles and/or to promote lipid transport and detoxification. This invention also provides a method of tracking a peptide in a mammal. In addition, the peptides inhibit osteoporosis. When administered with a statin, the peptides enhance the activity of the statin permitting the statin to be used at significantly lower dosages and/or cause the statins to be significantly more anti-inflammatory at any given dose.