Gary D. Gustafson,William Hoekstra,Michael R. Loso,Christopher M. Yates
申请号:
US14427785
公开号:
US20150246898A1
申请日:
2013.09.12
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes. Living organisms have developed tightly regulated processes that specifically import metals, transport them to intracellular storage sites and ultimately transport them to sites of use. One of the most important functions of metals such as zinc and iron in biological systems is to enable the activity of metalloenzymes.