Diderrich, Gaston,Bosse, Dietrich,Kiessling, Peter,Zeiss, Johannes
申请号:
AU2006334795
公开号:
AU2006334795B2
申请日:
2006.12.13
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention relates to the improvement of the transport properties of albumin which is produced on an industrial scale, e.g. via the Cohn process or by means of recombinant processes, and is mixed, during the production process, with substances that saturate the binding points on the albumin and thus affect the binding properties and transport properties of the final product. A special embodiment of the invention relates to pasteurized and then octanoate-reduced human albumin for therapeutic use, especially in a detoxification treatment of human plasma, e.g. for the intravenous treatment of acute or chronic liver diseases, and as a dialyzate in extracorporeal liver dialysis with albumin in the molecular adsorbent recirculating system (MARS) or in single-pass dialysis.