DE MIN CRISTINA,FERLIN WALTER,DE BENEDETTI FABRIZIO
申请号：
IN201727043024
公开号：
IN201727043024A
申请日:
2017.11.30
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
Methods and compositions for treating hemophagocytic lymphohistiocytosis (HLH) are provided. The disclosure also relates generally to methods and compositions for diagnosing and treating disorders associated with elevated levels of CXCL9 elevated levels of total IFN and other biomarkers. The disclosure also relates to methods of treating delaying the progression of or otherwise ameliorating a symptom of a disorder in patients with elevated levels of CXCL9 elevated levels of total IFN and other biomarkers using agents that interfere with or otherwise antagonize interferon gamma (IFN) signaling including neutralizing anti IFN antibodies.
