ERRICHELLI, LORENZO,GUPTA, DHANU,HEAN, JUSTIN,NORDIN, JOEL
申请号：
CA3082194
公开号：
CA3082194A1
申请日:
2018.11.08
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention pertains to extracellular vesicle (EV) therapeutics, wherein the EVs comprise nucleic acid (NA)-based therapeutics such as m RNAs, circular RNAs, mi RNAs, sh RNAs, circular RNA and/or DNA molecules. The NA therapeutics are loaded into EVs using inventive engineering protein and NA engineering strategies to enhance loading into EVs and to facilitate release of the NA cargo molecules inside target cells.
