NOVEL HETEROCYCLIC NITROGEN COMPOUNDS, THEIR PREPARATION AND THEIR USE AS ANTIBACTERIAL MEDICINES

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专利权人:

NOVEXEL

发明人:

BENOIT LEDOUSSAL,MARIE EDITH GOURDEL,EMILIE RENAUD,CAMILLE PIERRES,ADEL KEBSI

申请号：

FR0805602

公开号：

FR2937034B1

申请日:

2008.10.10

申请国别(地区):

FR

年份:

2012

代理人:

摘要：

The invention relates to nitrogenous heterocyclic compounds of formula (I): in which: R1 represents hydrogen, &mdash；(CH2)m&mdash；NH2, &mdash；(CH2)m&mdash；NH(C1-C6)alk, &mdash；(CH2)m&mdash；N(C1-C6)alk2, &mdash；(CH2)m&mdash；NH&mdash；C(NH)NH2 or &mdash；(CH2)m&mdash；NH&mdash；CH&boxH；NH, m is equal to 1 or 2； R2 and R3 together form a nitrogenous heterocycle of aromatic character with 5 vertices containing 1, 2 or 3 nitrogen atoms, substituted on a nitrogen atom by R4； R4 represents hydrogen, C1-C6)alk or a chain of formula: -(A)n-(NH)o&mdash；(CH2)p&mdash；(CHR&prime；)qR&Prime； A represents C&boxH；O, C&boxH；NH or SO2； R&prime； represents hydrogen or carboxy.

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