YOUNG, JAMES F.,KOENIG, SCOTT,JOHNSON, LESLIE S.,WU, HERREN,WATKINS, JEFFRY D.,HUSE, WILLIAM D.
申请号:
CA2430039
公开号:
CA2430039C
申请日:
2001.11.28
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention encompasses novel antibodies and fragments thereof whichimmunospecifically bind to one or more RSV antigens and compositionscomprising said antibody fragments. The present invention encompasses methodspreventing respiratory syncytial virus (RSV) infection in a human, comprisingadministering to said human a prophylactically effective amount of one or moreantibodies or fragments thereof that immunospecifically bind to one or moreRSV antigens, wherein a certain serum titer of said antibodies or antibodyfragments is achieved in said human subject. The present invention alsoencompasses methods for treating or ameliorating symptoms associated with aRSV infection in a human, comprising administering to said human atherapeutically effective amount of one or more antibodies or fragmentsthereof that immunospecifically bind to one or more RSV antigens, wherein acertain serum titer of said antibodies or antibody fragments is achieved insaid human subject. The present invention further encompasses compositionscomprising antibodies or fragments thereof that immunospecifically bind to aSRV antigen, and methods using said compositions for detection or diagnosis aRSV infection.