The Trustees of Columbia University in the City of New York
发明人:
CALIFANO, Andrea,ALVAREZ, Mariano, Javier
申请号：
HK19100052
公开号：
HK1257686A1
申请日:
2019.01.03
申请国别(地区):
HK
年份:
2019
代理人:
摘要：
Techniques to profile a disease or a disorder (e.g., a tumor) based on a protein activity signature are disclosed herein. An example method can include measuring quantitatively protein activity of a plurality of master regulator proteins in a sample from a disease or disorder； and profiling the tumor from the quantitative protein activity of the master regulator proteins. Also disclosed are methods of identifying a compound or compounds that treats diseases or disorders (e.g., inhibit tumor cell growth).
