COMPOSÉS (4'-HYDROXYPHÉNYL)CYCLOALCANE ET (4'-HYDROXYPHÉNYL)CYCLOALCÈNE SUBSTITUÉS ET LEURS UTILISATIONS EN TANT QU'AGONISTES SÉLECTIFS DE L'ISOFORME BÊTA DU RÉCEPTEUR DES STROGÈNES POUR UNE CONSOLIDATION AMÉLIORÉE DE MÉMOIRE
Concordia University, Inc.;Marquette University;The UWM Research Foundation, Inc
发明人:
申请号：
EP18776331.3
公开号：
EP3601204A1
申请日:
2018.03.30
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Disclosed are substituted (4'-hydroxylphenyl)cycloalkane compounds and substituted (4'-hydroxylphenyl)cycloalkene compounds and there use as selective agonists of the estrogen receptor beta isoform (ERβ). The disclosed compounds may be formulated as pharmaceutical compositions and administered for treating diseases associated with ER activity, such as neurological, psychiatric, and/or cell proliferative diseases and disorders as well as for enhancing memory consolidation in subjects in need thereof.
