BEDIAN, VAHE,DEVALARAJA, MADHAV NARASIMHA,LOW, JOSEPH EDWIN,MOBLEY, JAMES LESLIE,KELLERMANN, SIRID-AIMEE,FOLTZ, IAN,HAAK-FRENDSCHO, MARY
申请号:
NZ59545004
公开号:
NZ595450A
申请日:
2004.09.09
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
Provided is an anti-M-CSF monoclonal antibody or an antigen-binding portion thereof, wherein the antibody comprises a heavy chain with a specified amino acid sequence of monoclonal antibody 8.10.3F, without the signal sequence. The antibodies can be used to treat various cancers and diseases in which a high level of M-CSF causes malignancy.