Zhou Wang,Joel Byron Nelson,Minh Mindy Bao Nguyen,John S. Lazo,Paul A. Johnston,Peter Wipf
申请号：
US14351126
公开号：
US09708276B2
申请日:
2012.10.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A method for treating prostate cancer in a subject, comprising administering a therapeutically effective amount of at least one agent to the subject, wherein the agent is selected from:(a) a phenyl-substituted imidazole, or a pharmaceutically acceptable salt or ester thereof or(b) a compound, or a pharmaceutically acceptable salt or ester thereof, having a formula I of:wherein R20 is an aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a silyl-containing group, a boryl-containing group, a phosphine-containing group, amino, a thio-containing group, a seleno-containing group, halide, or a nitro-containing groupR21 is an alkanediyl or a substituted alkanediyla is 0 or 1c is 0 or 1X is C or SR22 is a moiety that includes at least one divalent amino radical andR23 is an aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a silyl-containing group, a boryl-containing group, a phosphine-containing group, amino, a thio-containing group, a seleno-containing group, halide, or a nitro-containing group.
