Andrew Patrick Rice,Sona Budhiraja,Hongbing Liu,Pei-Wen Hu
申请号：
US16489187
公开号：
US20200002724A1
申请日:
2018.02.26
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Embodiments of the disclosure concern systems, methods and compositions for generating Rev-dependent lentiviral vectors. In specific embodiments, the vectors are generated in a system that comprises Phosphofurin Acid Cluster Sorting protein 1 (PACS1) and/or Phosphofurin Acid Cluster Sorting protein 2 (PACS2). In embodiments, the vectors are utilized for therapeutic or research applications.
