Antisense Therapeutics Limited;Isis Pharmaceuticals, Inc.
发明人:
George Tachas,Kenneth Dobie,Ravi Jain,Christopher Belyea,Mark Heffeman
申请号：
US13655319
公开号：
US20130053431A1
申请日:
2012.10.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Compounds, compositions and methods are provided for modulating the expression of growth hormone receptor and/or insulin like growth factor-I (IGF-I). The compositions comprise oligonucleotides, targeted to nucleic acid encoding growth hormone receptor. Methods of using these compounds for modulation of growth hormone receptor expression and for diagnosis and treatment of disease associated with expression of growth hormone receptor and/or insulin-like growth factor-I are provided. Diagnostic methods and kits are also provided.
