George Tachas;Kenneth Dobie;Mark Heffernan;Ravi Jain;Christopher Belyea
发明人:
George Tachas,Kenneth Dobie,Ravi Jain,Christopher Belyea,Mark Heffernan
申请号：
US12953105
公开号：
US08623836B2
申请日:
2010.11.23
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Compounds, compositions and methods are provided for modulating the expression of growth hormone receptor and/or insulin like growth factor-I (IGF-I). The compositions comprise oligonucleotides, targeted to nucleic acid encoding growth hormone receptor. Methods of using these compounds for modulation of growth hormone receptor expression and for diagnosis and treatment of disease associated with expression of growth hormone receptor and/or insulin-like growth factor-I are provided. Diagnostic methods and kits are also provided.
