Board of Regents of the Nevada System of Higher Education on behalf of the University of Nevada; Reno
发明人:
Dean Burkin,Ryan Wuebbles,Pam Van Ry
申请号:
US14419063
公开号:
US09867866B2
申请日:
2013.08.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed herein are methods for diagnosing, prognosing and treating muscular dystrophy. Also disclosed are methods of determining the effectiveness of an agent for the treatment of muscular dystrophy. Provided are methods of enhancing muscle regeneration, repair, or maintenance in a subject by administering galectin, such as Galectin-1 and/or Galectin-3 to a subject in need thereof. Also disclosed are methods of increasing or maintaining muscle strength and/or bone density in a subject by administering an effective amount of a Galectin-1 composition, Galectin-3 composition or a combination thereof to the subject in need thereof. Methods of preventing, inhibiting and/or reducing muscle loss and/or bone loss in a subject by administering an effective amount of a Galectin-1 composition, Galectin-3 composition or a combination thereof to the subject in need thereof are disclosed.