ON BEHALF OTHE UNIVERSITY OF NEVADA; RENO;BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION; ON BEHALF OF THE UNIVERSITY OF NEVADA
发明人:
BURKIN, DEAN,WUEBBLES, RYAN,VAN RY, PAM
申请号：
CA2881532
公开号：
CA2881532A1
申请日:
2013.08.09
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Disclosed herein are methods for diagnosing, prognosing and treating muscular dystrophy. Also disclosed are methods of determining the effectiveness of an agent for the treatment of muscular dystrophy. Provided are methods of enhancing muscle regeneration, repair, or maintenance in a subject by administering galectin, such as Galectin-1 and/or Galectin-3 to a subject in need thereof. Also disclosed are methods of increasing or maintaining muscle strength and/or bone density in a subject by administering an effective amount of a Galectin-1 composition, Galectin-3 composition or a combination thereof to the subject in need thereof. Methods of preventing, inhibiting and/or reducing muscle loss and/or bone loss in a subject by administering an effective amount of a Galectin-1 composition, Galectin-3 composition or a combination thereof to the subject in need thereof are disclosed.
