Alexey Revenko;Gourab Bhattacharjee;Robert A. MacLeod
发明人:
Alexey Revenko,Gourab Bhattacharjee,Robert A. MacLeod
申请号：
US14129039
公开号：
US09322021B2
申请日:
2012.06.29
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Disclosed herein are methods for decreasing kallikrein and treating or preventing thromboembolic conditions in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to kallikrein include thrombosis, embolism, and thromboembolism, such as, deep vein thrombosis, pulmonary embolism, myocardial infarction, and stroke. Methods for inhibiting kallikrein can also be used as a prophylactic treatment to prevent individuals at risk for thrombosis and embolism.
