Monia, Brett P.,Crosby, Jeffrey R.,Zhao, Chenguang,Freier, Susan M.,Zhang, Hong
申请号:
AU2008323970
公开号:
AU2008323970B2
申请日:
2008.11.05
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
Disclosed herein are antisense compounds and methods for decreasing Factor7 and treating or preventing thromboembolic complications, hyperproliferativedisorders, or inflammatory conditions in an individual in need thereof. Examplesof disease conditions that can be ameliorated with the administration of antisensecompounds targeted to Factor 7 include thrombosis, embolism, and thromboembolism,such as, deep vein thrombosis, pulmonary embolism, myocardial infarction,stroke, cancer, rheumatoid arthritis, and fibrosis.