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NANOPARTICLE PLATFORM FOR ANTIBODY AND VACCINE DELIVERY
专利权人:
The Governing Council of the University of Toronto;The Hospital for Sick Children
发明人:
Jean-Philippe Julien,Taylor Sicard,Anthony Semesi,Bebhinn Treanor,Tiantian Zhao,Edurne Rujas Diez
申请号:
US16636141
公开号:
US20200179532A1
申请日:
2018.08.03
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A fusion protein comprises a nanocage monomer; and an antibody or fragment thereof linked to the nanocage monomer, the antibody or fragment thereof comprising a first member of a binding pair; wherein a plurality of the fusion proteins self-assemble to form a nanocage in which a plurality of the antibodies or fragments thereof decorate the exterior surface of the nanocage, whereby the first member of the binding pair is exposed for interacting with a second member of a binding pair.
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