An enhanced flow ophthalmic surgical probe for ophthalmic microsurgery, such as vitrectomy, in an eye of a patient is disclosed. The enhanced flow probe includes a body, a needle, a cutter, and an optional stiffening sleeve. The needle, the cutter, and the optional stiffening sleeve each possess a widened diameter at its proximal portion relative to the diameter at its distal portion, thereby providing an enhanced ophthalmic surgical probe that allows adequate stiffness, reduced flow resistance, and an increased flow rate while maintaining a less invasive, large gauge diameter needle and cutter.