The present invention relates to an oral pharmaceutical fixed dose composition in a form of a dispersible tablet for use in the treatment of tuberculosis, said oral pharmaceutical composition comprising: a) granules comprising isoniazid and at least one intragranular excipient, b) granules comprising rifapentine and at least one intragranular excipient, and c) at least one extragranular excipient, and to its process of preparation.本發明係關於一種用於治療肺結核之可分散錠劑型態之固定劑量之口服醫藥組合物,該口服醫藥組合物包含:a)包含異菸鹼醯胺及至少一種顆粒內賦形劑之顆粒,b)包含利福噴丁(rifapentine)及至少一種顆粒內賦形劑之顆粒,及c)至少一種顆粒外賦形劑,且關於其製備方法。
