Schaffer, David V.,Klimczak, Ryan R.,Koerber, James T.,Flannery, John G.,Dalkara Mourot, Deniz,Visel, Meike,Byrne, Leah C.T.
申请号：
AU2012245328
公开号：
AU2012245328B2
申请日:
2012.04.20
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells, when administered via intravitreal injection, compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease.
