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METHOD FOR INCREASING SUCTION OF UNSATURATED FATTY ACIDS IN BREAST CHILDREN
专利权人:
СВЕДИШ ОРФАН БИОВИТРУМ АБ (ПАБЛ) (SE)
发明人:
ХЕРНЕЛЛЬ Олле (SE),ОЛЬССОН Биргитта (SE),СТРЕМБЕРГ Патрик (SE),СВЕНССОН Леннарт (SE),ТИМДАЛЬ Кристина (SE),ВОГЕРЕ Мортен (SE),ЭМАН Мария (SE)
申请号:
RU2013123056/15
公开号:
RU2013123056A
申请日:
2010.10.21
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. Recombinant bile salt stimulated human lipase (rhBSSL) for use in a method for increasing absorption in a baby of at least one unsaturated fatty acid, said method comprising the step of enteral administration of a recombinant bile salt stimulated bile salt to said infant. RhBSSL for use according to claim 1, wherein said unsaturated fatty acid is selected from the group: a. essential fatty acid b. polyunsaturated fatty acid; c. an unsaturated fatty acid that has an aliphatic chain of 20 or more carbon atoms; and / or d. a polyunsaturated fatty acid that has an aliphatic chain of 20 or more carbon atoms (long chain polyunsaturated fatty acid - LCPUFA) .3. RhBSSL for use according to claim 1, wherein said at least one unsaturated fatty acid is an unsaturated fatty acid selected from the group consisting of: eicosadienoic acid (C20: 2 n-6), dihomo-gamma-linolenic acid ( C20: 3 n-6), eicosatrienoic acid (C20: 3 n-3), arachidonic acid (C20: 4 n-6) and docosahexaenoic acid (C22: 6 n-3), linoleic acid (C18: 2 n-6 ) and alpha-linolenic acid (C18: 3 n-3), preferably wherein said unsaturated fatty acid is arachidonic acid (C20: 4 n-6) and / or docosahexaenoic acid (C22 : 6 n-3) .4. RhBSSL for use according to claim 1, where, after administration of said lipase, vision development and / or cognitive development of said infant are improved. RhBSSL for use according to claim 1, where the specified lipase is administered in an amount per day from 1 to 100 mg of the specified lipase per kg of body weight of the infant, from 5 to 50 mg of the specified lipase per kg of body weight of the infant1. Рекомбинантная стимулируемая желчными солями липаза человека (rhBSSL) для применения в способе повышения всасывания у грудного ребенка, по меньшей мере, одной ненасыщенной жирной кислоты, причем указанный способ включает стадию энтерального введения рекомбинантной стимулируемой желчными солями липазы указанному грудному ребенку.2. RhBSSL для применения по п.1, где указанная ненасыщенная
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