In fibre-tracking from a diffusion weighted magnetic resonance image one or more regions-of-interest are selected from a high-resolution morphological magnetic resonance image. The geometrical relationship between the diffusion-weighted magnetic resonance image and the high-resolution magnetic resonance image is determined. Using the geometrical relationship, one or more region-of-interest corresponding to the anatomical structures represented in the high-resolution morphological image are identified and transferred to the diffusion weighted image space. These regions-of-interest in the diffusion-weighted images form the basis of a fibre tracking procedure. This yields fibre tracts that pass through the selected anatomical structures and enables functional interconnectivity analysis.