Rose Ann Padua,Christine Chomienne,Dominique Charron
申请号:
US12105831
公开号:
US08673870B2
申请日:
2008.04.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to the combination of a DNA vaccination strategy that makes use of a nucleic acid encoding an immunogenic polypeptide, with a non-immunosuppressive inducer of tumor cell differentiation and/or apoptosis or a tumor cell modifier, useful for cancer therapy. Vaccine compositions and kits are provided, as well as specific nucleic acid constructs that are particularly suitable for the preparation of such compositions.