Dérivés de benzothiadiazépine, procédés de leur préparation et compositions pharmaceutiques les contenant

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专利权人:

ALBIREO AB

发明人:

申请号：

EP03747171.1

公开号：

EP1501813B1

申请日:

2003.04.23

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention relates to compounds of formula (I): wherein R<；SUP>；v<；/SUP>；, R<；SUP>；1<；/SUP>；, R<；SUP>；2<；/SUP>；, R<；SUP>；x<；/SUP>；, R<；SUP>；y<；/SUP>；, R<；SUP>；3<；/SUP>；, R<；SUP>；4<；/SUP>；, R<；SUP>；5<；/SUP>；, R<；SUP>；6<；/SUP>；, R<；SUP>；z <；/SUP>；and v are as defined within； pharmaceutically acceptable salts, solvates, solvates or such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described.

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