Provide a method to more easily and accurately measure ADAs appearing in patients undergoing molecular target therapy such as medicine. A method for measuring ADAs in a sample to be measured including the following steps (1) to (4). (1) preparing a specimen containing a specimen to be measured of an ADAs body, and adding the medicament to a specimen to be measured of ADAs to prepare a specimen in which a medicine-ADAs immune complex is formed Step (2) a step of contacting the sample prepared in step (1) with a carrier obtained by immobilizing complement C1q, an anti-C3d antibody or an anti-C1q antibody, (3) a step of bringing a labeled or unlabeled antibody to a drug corresponding to said ADAs into contact with the solid phase carrier prepared in step (2) (4) Step of Quantifying Drug-ADAs Immunoconjugate Bound to Complement C1q, Anti-C3d Antibody or Anti-C1q AntibodySelection drawing None医薬品による分子標的療法などを受けている患者において出現するADAsを、より簡便に且つ正確に測定する方法の提供。 以下の工程(1)~(4)を含む、被測定検体中のADAsの測定方法。 (1)ADAs体の被測定検体を含む試料を準備する工程であって、ADAsの被測定検体に当該医薬品を添加して、医薬品-ADAs免疫複合体が形成された試料を調製することを含む工程 (2)補体C1q、抗C3d抗体又は抗C1q抗体を固相化した担体に、工程(1)で調製した試料を接触させる工程 (3)工程(2)で作製された固相担体に、前記ADAsに対応する医薬品に対する標識又は非標識抗体を接触させる工程 (4)補体C1q、抗C3d抗体又は抗C1q抗体に結合した医薬品-ADAs免疫複合体を定量する工程【選択図】なし
