PROBLEM TO BE SOLVED: To provide a new ACE inhibitory peptide that effectively inhibits ACE with a small amount of intake, has no fear of adverse effects and allows a person with hypertension to easily take by mouth in a daily life, an angiotensin-converting enzyme inhibitor comprising the peptide, a composition and a food, and a method for producing the peptide.SOLUTION: There are provided a peptide comprising an amino acid sequence shown by any of the following (1)-(8) of (1) Phe-Phe-Tyr-Tyr, (2) Trp-His-Pro, (3) Phe-Val-Pro, (4) Leu-His-Pro-Gly-Asp-Ala-Glu-Arg, (5) Ile-Ala-Val, (6) Val-Asn-Pro, (7) Leu-Glu-Pro-Pro and (8) Trp-Asn-Pro-Arg, and having angiotensin-converting enzyme inhibitory activity, and a salt thereof.COPYRIGHT: (C)2013,JPO&INPIT【課題】少量の摂取でACEを有効に阻害し、かつ副作用の心配が無く、高血圧者が日常生活の中で容易に経口摂取できる新規のACE阻害ペプチド、及びこれらのペプチドを含むアンジオテンシン変換酵素阻害剤、組成物及び食品、並びにその製造法を提供すること。【解決手段】下記(1)~(8)のいずれかで表されるアミノ酸配列からなり、アンジオテンシン変換酵素阻害活性を有するペプチドおよびその塩。(1)Phe-Phe-Tyr-Tyr、(2)Trp-His-Pro、(3)Phe-Val-Pro、(4)Leu-His-Pro-Gly-Asp-Ala-Glu-Arg、(5)Ile-Ala-Val、(6)Val-Asn-Pro、(7)Leu-Glu-Pro-Pro、(8)Trp-Asn-Pro-Arg。【選択図】なし
