PRIMO RAMOS, DANIEL,BALLESTEROS NOBELL, JUAN ANTONIO,BENNETT, TERESA ANN,GORROCHATEGUI GUILLEN, JULIAN,MARTINEZ LOPEZ, JOAQUIN,VALERI LOZANO, ANTONIO,LEIVAS ALDEA, ALEJANDRA
申请号：
CA3079310
公开号：
CA3079310A1
申请日:
2018.10.18
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The CAR-T cells described herein can provide highly effective therapies for diverse cancer types, e.g., solid cancers, hematological cancers, and metastatic forms thereof. Provided herein are methods of generating CAR-T cells, compositions comprising such CAR-T cells, methods of treatment using the cells, methods of identifying subjects susceptible to immune checkpoint immunotherapy treatment and methods of evaluating susceptibility of a subject to develop Cytokine-Release Syndrome.
