ROCHE INNOVATION CENTER COPENHAGEN A/S;BRISTOL-MYERS SQUIBB COMPANY
发明人:
Richard E. Olson,Angela M. Cacace,Peter Hagedorn,Anja Mølhart Høg,Marianne Lerbech Jensen,Niels Fisker Nielsen,Dong Li,Jeffrey M. Brown,Stephen E. Mercer
申请号：
US15549021
公开号：
US20180161356A1
申请日:
2016.02.04
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to oligomer compounds (oligomers), which target Tau mRNA in a cell, leading to reduced expression of Tau protein. Reduction of Tau protein expression is beneficial for the treatment of certain medical disorders, e.g., a neurological disorder.
