Roche Innovation Center Copenhagen A/S;Bristol-Myers Squibb Company
发明人:
Jensen, Marianne Lerbech,Nielsen, Niels Fisker,Li, Dong,Brown, Jeffrey M.,Mercer, Stephen E.,Olson, Richard E.,Cacace, Angela M.,Hagedorn, Peter,Hog, Anja Molhart
申请号:
AU2016215155
公开号:
AU2016215155A1
申请日:
2016.02.04
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention relates to oligomer compounds (oligomers), which target Tau mRNA in a cell, leading to reduced expression of Tau protein. Reduction of Tau protein expression is beneficial for the treatment of certain medical disorders, e.g., a neurological disorder.