Refers to a compound of formula (i), where a is ntrogeno, CR5 R5 is H, Chlorine, iodine, among others r1 is H, fluoride, among others R2 is alkyl, benzyl) - 1, - trifluoroprop - ILO, among others R3 is H, cyano, alkoxy, between other alkyl R4 is difluorometilo, trifluoromethyl, among others L # cr6ar6b - (1 - cr7ar7b) # # M - 2, where 1 is the point of attachment to the carbonyl Group# 2 is the point of attachment to the pyrimidine or triazine ring, M is 0 - 2 r6a is H, alkyl, Fluorine, among others R6B is difluorometilo, trifluoromethyl, among others R7a Fluorine, Hydrogen, alkyl, etc. R7b is Hydrogen, alkyl, cyano, among others.Preferred compounds are 2 - [1 - (2-fluorobenzyl) - 1H pyrazolo [3,4-b] pyridin-3-yl] - 4 - (3-methoxypropyl) - 5,5 - Dimethyl 5,7 - dihydro - 5h pyrrolo [2,3-d] pyrimidine - 6 - methyl - 5 - One 6 oxo - 2 - [1 - (3,3,4,4,4 - pentafluorobutil) - 1H pyrazolo [3,4-b] pyridin-3-yl] - 6.7 - dihydro - 5h pyrrolo [2,3-d] pyrimidine 5 - carboxylate Ethyl Among others.This Compound is useful for the treatment and Prevention of cardiovascular disorders.SE REFIERE A UN COMPUESTO DE FORMULA (I), DONDE A ES NTROGENO, CR5 R5 ES H, CLORO, YODO, ENTRE OTROS R1 ES H, FLUOR, ALQUILO, ENTRE OTROS R2 ES BENCILO, 3,3,3-TRIFLUOROPROP-1-ILO, ENTRE OTROS R3 ES H, CIANO, ALCOXI, ENTRE OTROS R4 ES ALQUILO, TRIFLUOROMETILO, DIFLUOROMETILO, ENTRE OTROS L ES #1-CR6AR6B-(CR7AR7B)m-#2, DONDE #1 ES EL PUNTO DE UNION AL GRUPO CARBONILO, #2 ES EL PUNTO DE UNION AL ANILLO PIRIMIDINA O TRIAZINA, m ES 0-2 R6A ES H, FLUOR, ALQUILO, ENTRE OTROS R6B ES DIFLUOROMETILO, TRIFLUOROMETILO, ENTRE OTROS R7A ES HIDROGENO, FLUOR, ALQUILO, ENTRE OTROS R7B ES HIDROGENO, CIANO, ALQUILO, ENTRE OTROS. SON COMPUESTOS PREFERIDOS 2-[1-(2-FLUOROBENCIL)-1H-PIRAZOLO[3,4-b]PIRIDIN-3-IL]-4-(3-METOXIPROPIL)-5,5-DIMETIL-5,7-DIHIDRO-6H-PIRROLO[2,3-d]PIRIMIDIN-6-ONA 5-METIL-6-OXO-2-[1-(3,3,4,4,4-PENTAFLUOROBUTIL)-1H-PIRAZOLO[3,4-b]PIRIDIN-3-IL]-6,7-DIHIDRO-5H-PIRROLO[2,3-d]PIRIMIDIN-5-CARBOXILATO DE ETIL
