MEMORIAL SLOAN KETTERING CANCER CENTER;LUDWIG INSTITUTE FOR CANCER RESEARCH LTD;AGENUS INC.
发明人:
VAN DIJK, MARC,MUNDT, CORNELIA ANNE,RITTER, GERD,SCHAER, DAVID,WOLCHOK, JEDD DAVID,MERGHOUB, TAHA,WILSON, NICHOLAS STUART,SAVITSKY, DAVID ADAM,FINDEIS, MARK ARTHUR,ZAPPASODI, ROBERTA,HOLMGAARD, RIKKE
申请号：
CA3046082
公开号：
CA3046082A1
申请日:
2017.12.07
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Provided are antibodies that specifically bind to CTLA-4 and/or PD-1 and antagonize CTLA-4 and/or PD-1 function. Also provided are pharmaceutical compositions and kits comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies either alone or in combination.
