As -4H pyrazolos [3, the 4-d] pyrimidin-4-one of the 1 of PDE1 inhibitor, 5 dihydro and 1, -4H pyrazolos [4,3-c] pyridin-4-one of 5 dihydros

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专利权人:

H. LUNDBECK A/S

发明人:

JAN KEHLER,KARSTEN JUHL,MORTEN LANGGÅRD,MAURO MARIGO,MIKKEL JESSING,PAULO JORGE VIEIRA VITAL,LARS KYHN RASMUSSEN

申请号：

DO2018000201

公开号：

DOP2018000201A

申请日:

2018.09.19

申请国别(地区):

DO

年份:

2018

代理人:

摘要：

The present invention provides 1,5- dihydro -4h- pyrazolos [3,4-D] pyrimidin-4-ones and 1,5- dihydro -4h- pyrazolos [4,3-c] pyridin-4-one formula (I) as PDE1 inhibitor and their purposes as drug, be especially used to treat neurodegenerative disorders and mental disease.La presente invención proporciona 1,5-dihidro-4H-pirazolo[3,4-d]pirimidin-4-onas y 1,5-dihidro-4H-pirazolo[4,3-c]piridin-4-onas de fórmula (I) como inhibidores de PDE1 y su uso como un medicamento, en particular para el tratamiento de trastornos neurodegenerativos y trastornos psiquiátricos.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/